Why Do I Feel So Tired All the Time?

One of the most common symptoms of hormone imbalance is fatigue. For many women experiencing the wild roller coaster ride of hormonal ups and downs during perimenopause, it can be utterly exhausting. Men often feel that same weary, lethargic, low energy fatigue when their testosterone levels dip below normal.
Both men and women can also experience what is called crashing fatigue as part of testosterone deficiency or perimenopause. This extreme tiredness and lethargy can hit suddenly and unexpectedly. It can occur at any time of day and is unrelated to recent physical exertion. Crashing fatigue has been described as abrupt overwhelming feelings of weakness, exhaustion and diminished energy level.

Unfortunately, the disruptive saga of fatigue continues. There are generally other symptoms that accompany hormone deficiency-related fatigue. Daytime sleepiness is often followed by nighttime sleeplessness. Night sweats and hot flushes are frequently blamed for the sleep interruptions. Sleep deprivation, in turn, can create mood changes, irritability, depression and difficulty in managing the daily routine. It can also raise the risk of high blood pressure, Alzheimer’s, heart disease, stroke, diabetes, obesity and other health issues.

It looks like a bleak picture, but it doesn’t have to be.

Bioidentical Hormone Pellet Therapy Can Relieve Debilitating Fatigue

There is good news for the thousands of men and women who suffer with hormone deficiency-related fatigue and other symptoms. Bioidentical hormone pellet therapy, when properly administered, can help restore hormonal balance and alleviate symptoms, including fatigue.

Estrogen and testosterone are essential hormones that perform hundreds of tasks throughout the body. They work synergistically with other hormones to provide you with the energy and well-being your body needs to perform at its best. The hormone loss and deficiency of andropause and menopause rob you of your vitality, motivation and even your health.

Why suffer when SottoPelle® BHRT can help you regain your life? Our pellet implant therapy provides just the right amounts of humanly identical hormones in a way that your body can work with and utilize. We are experts at tailoring hormone replacement to meet your individual needs. Call us today to schedule a consultation and join thousands of others who can enjoy life again because of SottoPelle®.

How to Maximize Your Brain Power While on BHRT

BHRT Restores Key Hormones

Once you have chosen bioidentical hormone replacement using pellet therapy, you’ve already gone a long way towards supporting a healthy brain. That’s because your sex hormones—estradiol, progesterone and testosterone—remain essential throughout your life and are especially good for your brain. When they diminish and disappear at menopause and andropause, it changes the way your brain works. You may experience moodiness, negativity, depression, foggy thinking, memory loss, trouble concentrating, forgetfulness and other cognitive issues.

Healthy, youthful levels of hormones, on the other hand, work synergistically to protect brain function and keep your mind sharp as you age. Research studies are ongoing, but considerable data exists to support the important role in cognitive health played by key hormones. 1,2,3

Maximizing Brain Power as You Age

BHRT is only one piece of the puzzle. The other piece is you. There are known risk factors for what is called age-related cognitive decline. Lack of physical activity, excess body weight, chronic low-level inflammation and uncontrolled high blood pressure are examples. So what can you do that is proactive and possibly preventive?

Diet. Focus on nutrient dense whole foods that are rich in fiber, vitamins, minerals, antioxidants, omega 3 fatty acids and other beneficial substances. Some great brain foods include beets, spinach, walnuts, celery, dark chocolate, apples, cinnamon, chia seeds and turmeric.

Physical Exercise. This is perhaps the best elixir you could take to improve your memory and alertness, and for building new brain cells. Exercise increases circulation and metabolism, lowers stress and elevates mood. Research has shown that physical exercise can both prevent later-life dementia4 and improve memory and learning in older adults.5

Mental exercise. Like your muscles, your brain needs to be stretched to keep it supple and strong. The best brain boosting activities take you out of your comfort zone to learn something new and unfamiliar. If it isn’t challenging, you aren’t stretching enough. Pick an activity that is mentally demanding, engaging and requires effort.

There are plenty of helpful online resources with many more suggestions on how to keep your brain healthy. For a starting point, check out some ideas at the Open Education Database, http://oedb.org/ilibrarian/100-ways-to-keep-your-mind-healthy/.


1 Antonella Gasbarri; Assunta Pompili; Maria Clotilde Tavares; Carlos Tomaz. Estrogen and Cognitive Function. Expert Rev Endocrinol Metab. 2009;5(5):507-520.
2 Brinton RD, Thompson RF, Foy MR, Baudry M, Wang J, Finch CE, Morgan TE, Pike CJ, Mack WJ, Stanczyk FZ, Nilsen J. Progesterone receptors: form and function in brain. Front Neuroendocrinol. 2008 May;29(2):313-39. doi: 10.1016/j.yfrne.2008.02.001. Epub 2008 Feb 23.
3 Zitzmann M. Testosterone and the brain. Aging Male. 2006 Dec;9(4):195-9.
4 Laura F. DeFina, Benjamin L. Willis, Nina B. Radford, Ang Gao, David Leonard, William L. Haskell, Myron F. Weiner, Jarett D. Berry. The Association Between Midlife Cardiorespiratory Fitness Levels and Later-Life Dementia: A Cohort Study. Annals of Internal Medicine, 5 February 2013, Vol 158, No. 3.
5 Gregory MA, Gill DP, Petrella RJ. Brain health and exercise in older adults. Curr Sports Med Rep. 2013 Jul-Aug;12(4):256-71. doi: 10.1249/JSR.0b013e31829a74fd.

Can Hormone Deficiency Cause Weight Gain?

Yes. Perhaps one of the most discouraging parts of approaching menopause is the weight gain. In fact, almost 90% of women between the ages of 35 and 55 gain weight. Total body fat increases, especially around the waistline, while at the same time lean muscle mass decreases. The same is true for men experiencing andropause.
Hormone imbalance makes it difficult to maintain a healthy weight. For women, waning estrogen levels often trigger the body to store fat. According to medical research, hormone loss does even more damage. Diminished estrogen levels or a lessening of estrogen receptor function in women also raises the risk for developing insulin resistance1, increased belly fat, 2,3 liver dysfunction, 4,5 and skeletal muscle dysfunction.6,7 Low levels of total, bioavailable and free testosterone in both men and women are likewise scientifically linked to increased risk of various diseases including cardiovascular disease, atherosclerosis and even mortality8. Bone mass, muscle mass, strength, libido and sex drive are also negatively impacted by testosterone deficiency.

Combatting weight gain begins with restoring your hormones to youthful levels.

Correctly administered bioidentical hormone replacement therapy can be your path to regaining and maintaining a healthy weight and increased well-being as you age. Make sure you see a physician who is expert in balancing hormones. We recommend using the pellet implant method as it is scientifically proven to be the safest and most effective BHRT method available.9,10,11,12 This technique is the closest thing we have to the way the body works, especially when given in individualized doses. And it is the only delivery system that allows the body to control the release of the hormone so that during vigorous exercise or increased stress when you need more hormone, you’re capable of getting it.

Eating healthy and getting regular exercise must be a priority.

When you combine the pellet method of hormone restoration with a new exercise regime and a healthy diet, remarkable things can happen. Once your estrogen (i.e. estradiol) and testosterone levels are returned to consistent, healthy, youthful levels, you’ll find your motivation to exercise return. Additionally, you’ll begin to notice results from your workouts, lose your foggy thinking and grumpy, apathetic, stay-at-home attitude. Like so many others, you’ll feel like you’ve regained your life!


1 Gorres BK, Bomhoff GL, Morris JK, Geiger PC. In vivo stimulation of estrogen receptor-alpha increases insulin-stimulated skeletal muscle glucose uptake. J. Physiol. 2011; 589(Pt 8):2041–54.
2 Wohlers LM, Jackson KC, Spangenburg EE. Lipolytic signaling in response to acute exercise is altered in female mice following ovariectomy. J. Cell. Biochem. 2011; 112(12):3675–84.
3 Wohlers LM, Spangenburg EE. 17Beta-estradiol supplementation attenuates ovariectomy-induced increases in ATGL signaling and reduced perilipin expression in visceral adipose tissue. J. Cell. Biochem. 2010; 110(2):420–7.
4 Jackson KC, Wohlers LM, Valencia AP, et al. Wheel running prevents the accumulation of monounsaturated fatty acids in the liver of ovariectomized mice by attenuating changes in SCD-1 content. Appl. Physiol. Nutr. Metab. 2011; 36(6):798–810.
5 Lavoie JM, Pighon A. NAFLD, estrogens, and physical exercise: the animal model. J. Nutr. Metab. 2012; 2012:914938.
6 Moran AL, Nelson SA, Landisch RM, Warren GL, Lowe DA. Estradiol replacement reverses ovariectomy-induced muscle contractile and myosin dysfunction in mature female mice. J. Appl. Physiol. 2007; 102(4): 1387–93.
7 Sitnick M, Foley AM, Brown M, Spangenburg EE. Ovariectomy prevents the recovery of atrophied gastrocnemius skeletal muscle mass. J. Appl. Physiol. 2006; 100(1):286–93.
8 Morgentaler A, Miner MM, Caliber M, Guay AT, Khera M, Traish AM. Testosterone therapy and cardiovascular risk: advances and controversies.Mayo Clin. Proc. 2015;90(2):224-251.
9 Salmon U, et. al.: Use of estradiol subcutaneous pellets in humans. Science 1939,90:162.
10 Mishel, D: Clinical study of estrogenic therapy with pellet implantation. Am J Obstet-Gynecol 1941:41:1009.
11 Studd, J: Estradiol and testosterone implants in the treatment of psychosexual problems in postmenopausal women. Br J Obstet Gynaecol 1977:84:314.
12 Greenblatt, R: Indications for hormone pellets in the therapy of endocrine and gynaecological disorders. American J Obstet Gyn, 1949:57:294.

5 Key Ways to Take Charge of Your Health as You Age

A respected physician who works on a Phoenix area Indian reservation tells his diabetic patients that out of the 8,760 hours there are in a year, they see their health care providers on average only 10 of those hours. That leaves more than 99% of the time that they, the patients, are in charge of their own health. After all, it is their health. It’s the doctor’s responsibility to help patients understand how to do the best job possible to manage it.
Great perspective and great advice that is relevant to all of us. We are the deciders when it comes to our well-being.

Here are a few ways to help you take charge of your own health as you age:

1) Educate yourself. The Internet is both a blessing and a curse. You have an unlimited resource at your fingertips, but there’s also a lot of misinformation. Read widely but with a healthy skepticism. Remember, there’s never just one answer to good health and one study does not establish a scientific truth. You are unique and what works for someone else, may not be right for you. Nonetheless, be informed and do your homework.

2) Do some serious soul searching. What are your biggest health hurdles? Do you have any serious conditions or minor ones that could become serious? Are you overweight? Do you exercise enough? Do you see your doctor for regular checkups? Are you worried about your health as you age? What are you willing to do to be healthy? Do you have the discipline to make changes and stick to them? Once you’ve surveyed your status quo, make a checklist and then make a sincere commitment to take steps.

3) Food is your ally. An abundance of long term studies and surveys continue to show a strong connection between diet and disease. In other words, what you eat can influence whether you fall victim to many aging-related illnesses like type 2 diabetes, cardiovascular disease, cancer, osteoporosis, and others. Some good reads on the topic include Dr. Neal Barnard’s Program for Reversing Diabetes. In this evidence-based book, author and clinical researcher, Dr. Neal Barnard, explains the nutrition-diabetes relationship. Dr. Caldwell B. Esselstyn, Jr. presents a strong argument for implementing a plant-based diet in Prevent and Reverse Heart Disease. Perhaps the most compelling case for adopting a healthy diet is The China Study, authored by Drs. T. Colin Campbell and Thomas M. Campbell II. This comprehensive study of nutrition has been called “one of the most important books about nutrition every written.”

4) Exercise. Science shows that exercise at any age or stage of life will benefit you. And it’s never too late to start an exercise program. Join a gym, sign up for yoga or get together with friends for morning walks. You’ll find that the benefits of exercise are instantaneous and invigorating. Remember, it doesn’t have to be strenuous to be beneficial. When you do something as simple as walking, it raises your heart rate, increases your respiration, burns calories and gives your muscles a workout.

5) Hormonal balance is vital. Your long term health depends on more than just diet and exercise. Hormonal balance is key to maintaining many important internal body functions. As you age, the production of certain vital hormones—i.e. estradiol and testosterone—stops or slows down. You need physiologic levels of these hormones to stay healthy. They impact every system, cell, gland and organ in your body. Your brain, muscles, bones, heart, lungs, and so on, all depend on hormones to keep them healthy. As an essential part of managing your health as you age, see a hormone replacement expert like SottoPelle® to have your hormone health checkup.

Hey Guys – It’s Time to Schedule Your Annual Checkup!

Men’s Health Month is nearly over, we’re going to nag you a little. When was the last time you scheduled your annual checkup? If you’re the average male, it’s probably been a while. In fact, according to the CDC, men are 100% less likely to get their yearly exams and preventive care than women.1 Millions of men don’t even have a regular doctor they see. How can that be?
Why Do Most Men Avoid Regular Check-ups?

There are obviously as many reasons for staying away from the doctor as there are men. Some men say it’s inconvenient to take time off from work, or they won’t go unless something is wrong, or sometimes they’re worried that the doctor will indeed find something wrong. For the most part, men simply aren’t programmed to think they need to see the doctor for regular exams.
So you’re not alone in your avoidance, but you’re missing out on the best chance you have at preventing or early detection of conditions like heart disease, stroke, cancer or COPD.

Why Are Annual Medical Examinations So Important For Men?

Preventive care is one of the best favors you can do for yourself, especially if you are over age 40. Did you know that almost 133 million Americans are living with a chronic disease or condition and many aren’t even aware of their condition?2 The four diseases mentioned above—heart disease, stroke, cancer and COPD—also happen to be the leading causes of death in men. What most men don’t realize is that these and many other conditions are highly preventable and very treatable if detected early.

4 Good Reasons to Schedule Your Annual Checkup:

1) Stop health problems before they develop. Good preventive care obviously begins before you get sick. A lot of physicians are starting to focus on more than just treating illness. The emphasis has now shifted to prevention. Abundant scientific evidence shows that many diseases can be avoided altogether or even healed by adopting a healthy lifestyle. By seeing your doctor annually, he or she can help you monitor changes in your weight, blood pressure, blood sugar, cholesterol, hormone levels and other key health gauges.

2) Some diseases don’t warn you until it’s too late. Did you know that high cholesterol and high blood pressure don’t have obvious symptoms to alert you? Yet, both of these conditions, if left untreated, put you at greater risk of heart attack and stroke. Type 2 diabetes can also appear without warning. The same goes for prostate and colon cancers which can progress to advanced stages before presenting symptoms. If you’re waiting to see the doctor until you feel sick, you’re playing a dangerous game with your health.

3) Your health is a great investment. Investing in good health will actually save you a ton of money. When you get sick, especially with a chronic illness, it costs you time and money. Time away from work combined with your medical and pharmaceutical bills can leave you with an insurmountable pile of debt. In fact, study published in the American Journal of Medicine in 2007, showed that illness and medical bills contribute to a large and increasing share of US bankruptcies.3

4) What you don’t know might cost you your life. Plain and simple, seeing your doctor annually might save your life. Chronic disease is known to cause 7 out of every 10 deaths.4 So why take the chance? Even if you don’t have any complaints, the annual exam is a great way to help you maintain good health or get you on track with making important changes in the way you live your life.


1 http://www.cdc.gov/nchs/pressroom/01news/newstudy.htm
2 http://www.fightchronicdisease.org/sites/default/files/docs/GrowingCrisisofChronicDiseaseintheUSfactsheet_81009.pdf
3 http://www.pnhp.org/new_bankruptcy_study/Bankruptcy-2009.pdf
4 http://www.cdc.gov/chronicdisease/overview/

Have You Had Your Thyroid Checked Lately?

Most men and women know something about aging-related estrogen and testosterone deficiencies, but what about thyroid hormones? The thyroid is also an important part of your endocrine system. In fact, it plays a central role in your health. Its control over metabolism affects nearly every cell and organ in the body. The thyroid also regulates body temperature, growth, muscle strength, appetite, and the health of your heart, brain, kidneys and reproductive system.
As you get older, thyroid function begins to slow down. Unfortunately, under-active thyroid (hypothyroidism) is difficult to diagnose. The symptoms are often vague and develop so slowly that many people don’t even know they have it. It was estimated in 2009 that nearly 4.6 percent of our populace aged 12 and up has hypothyroidism. According the American Thyroid Association, more than 12 percent of the U.S. population will develop a thyroid condition during their lifetime. Women are statistically more likely than men to develop hypothyroid and it’s also more widespread in people over age 60.

Indications That You Should Have Your Thyroid Checked

The most common symptoms of hypothyroidism are:
• Low energy
• Fatigue or exhaustion, even after a full night’s sleep
• Cold and heat intolerance
• Decreased sweating
• Dry skin
• Weight gain
• Puffy face
• Dry, thinning hair
• Depression
• Slowed heart rate

Other signs of hypothyroidism may include:
• High cholesterol
• High blood pressure
• Digestive problems
• Constipation
• Circulatory problems
• Anemia
• Allergies
• Frequent infections
• Sleep disturbances
• Muscle weakness
• Acne
• Eczema
• Infertility
• Premenstrual syndrome
• Memory loss
• Difficulty losing weight
• Fuzzy brain
• Difficulty concentrating or forgetfulness
• Low libido

You may have several of these or even none at all. The only way to know for sure is to see a doctor and have your thyroid checked. Since these symptoms can also be related to other health problems, it’s imperative to have a thorough health check to determine what’s going on. You’ll need comprehensive blood tests, including thyroid and other endocrine hormone panels. If you’re over 50, you may find your doctor writing off your complaints as a part of “normal aging.” Find another physician who will take your situation seriously.

3 Reasons You Aren’t Sleeping Well

On average, you need at least 6 hours of sleep to waken feeling fully rested. It’s been shown to encourage sleep if you go to bed at the same time each night, which should be around 10:30 to 11 p.m. It’s also a good idea to rise around the same time each morning. Earlier is better than later.
Most of us experience sleep issues at one time or another during our lives. But as you get older you may find that happening on a regular basis. Your insomnia may even become chronic and take its toll on your health. Let’s take a look at what could be causing you to toss and turn, and some things you can do that will help.

Why You Aren’t Sleeping Well

1) PROBLEM: Too much TV!
Insomnia has been linked to excessive TV watching. It seems that overexposure to the bright light emitted from your TV screen (or your iPad or smartphone for that matter) can negatively affect your melatonin production. It’s thought that using these devices at night tricks the brain into thinking it isn’t time for sleep.

SOLUTION: Cut off the TV or other devices at least an hour before bedtime, preferably two. You might also want to remove all of your electronics from your bedroom and use this room just for sleeping. Instead of watching TV, read an inspirational book, listen to relaxing music, or use this quiet time for meditation or prayer before retiring to the bedroom.

2) PROBLEM: Too much to drink!
Alcohol can make you drowsy and help you fall asleep, but it deprives you of the deep sleep you really need. A glass of wine with dinner won’t put a dent in your slumber. However, consuming several drinks before bedtime can have you waking in the middle of the night, unable to get back to sleep. If you frequently drink before bed, you will find yourself chronically drained and exhausted from lack of deep sleep.

SOLUTION: Alcohol should not be used as a sleep aid. Nor should you depend on medications, which also rob you of REM sleep. Instead, create a new relaxation routine that will encourage sleep. You might want to begin an exercise regime that gets you outside during the day. Merely walking at a moderate pace for a half hour daily can reduce the time it takes to fall asleep, help you sleep longer and get better quality sleep.

3) PROBLEM: Not enough hormones!
Problems with endocrine hormones affect both men and women who are experiencing perimenopause, menopause or andropause. At this stage of life, hormonal imbalance prevails. Insomnia is a typical side effect of fluctuating or depleted hormones.

SOLUTION: Get your hormones checked! If you are deficient in testosterone, estradiol or thyroid, you can likely benefit from a safe and effective bioidentical hormone replacement therapy such as SottoPelle®. Not only will it alleviate symptoms of hormone deficiency and help you get better rest, our BHRT is the perfect foundation for a healthier, happier life as you age.

BHRT & Weight Control – What Can be Done?

Endocrine hormones are vital to good health. They impact cells, organs and tissues throughout your body. When menopause or andropause occurs, you become hormone deficient. A woman no longer produces estradiol (her most important estrogen), and a man’s ability to make testosterone slows down dramatically. Endocrine hormone deficiency depletes the body of these vital substances and impacts many body functions negatively, including weight control. It’s a time of life when you become more susceptible to diseases like diabetes, cardiovascular disease, osteoporosis, Alzheimer’s and others.
When estradiol and/or testosterone are restored to beneficial levels using properly administered bioidentical hormone pellet therapy, such as our proprietary SottoPelle® method, your body can once again thrive. In fact, properly balanced hormones can make it easier for you to lose weight and keep it off. How so, you ask?

BHRT & Weight Control

1. Hormonal Balance means better sleep. Research has linked sleep deprivation with obesity, diabetes, high blood pressure and depression. Estrogen is a key sleep-supporting hormone. Beneficial testosterone levels allow for deeper sleep. More hours of sleep will help lower your cortisol level, which can result in weight loss.

2. Testosterone Replacement can increase muscle mass and help you lose fat. Both men and women suffer from muscle wasting as they age. At the same time, low testosterone contributes to the “fat tire” around your middle. Achieving healthy blood levels of testosterone through BHRT can help burn fat. You’ll once again see positive results from exercise and working out.

3. Healthy Hormone Levels increase metabolism, restore energy, boost motivation and are key to fitness, weight loss and maintaining a healthy lifestyle. On the flip side, hormone deficiency decreases your quality of life. Estrogen deficiency has been linked to slow metabolism. Hormonal imbalance increases the likelihood of depression, low energy, and lack of motivation, all of which contribute to weight gain or inability to lose unwanted weight.

**If you want to see if BHRT can help you with weight control, click here to take a self-assessment quiz.

What is the Main Reason Women Use SottoPelle®?

perimenopause and post-menopause symptoms treatment with SottoPelle

Although there are many reasons why women use SottoPelle, the primary goal is to relieve perimenopause and post-menopause symptoms. Losing hormones as a woman can strain one’s overall well-being and quality of life. Especially with age, this becomes much more difficult when facing menopause. That’s where SottoPelle? Therapy comes in.

When is Perimenopause and When Does it Happen to Women?

Perimenopause can occur anytime between the ages of 30 and 50 for women. This is due to hormone imbalance. A woman’s ovaries start to function differently at this period in life, which causes the ovaries to produce less estrogen. This change and imbalance often comes with several side effects, including the following:

What are you need to look out for with Perimenopause

  • Perimenopause
  • A woman may begin to gain weight easier
  • Night sweats and hot flashes
  • Irregular mood swings that may lead to depressions
  • Decreased sexual performance
  • And more

What is Menopause?

Menopause is the end of the female reproductive cycle and is commonly diagnosed when a woman has not had her period for 12 months. The average age for the onset of Menopause is 51 but can also happen in as early as your late 30’s. The precise method of determining if a woman is in Menopause is to measure the amount of follicle stimulating hormone levels in the blood. Leading up to Menopause, the ovaries produce fewer hormones, which cause a variety of changes in a woman’s body.

Surgical removal of the ovaries and other medical conditions and treatments can also induce Menopause. The fluctuations in the hormones estrogen, testosterone and progesterone can cause your periods to become irregular and sometimes heavy. Other symptoms like hot flashes, night sweats, mood swings, brain fog, and headaches can soon follow.

Menopause Symptoms

  • Brain Fog
  • Low Sexual Desire
  • Dry Skin
  • Headaches
  • Vaginal Dryness
  • Hair Loss
  • Increased Body Fat
  • Anxiety
  • Fatigue & Lower Energy Levels
  • Depression

Why Women Use SottoPelle

Menopause is something that women often dread, and rightfully so. However, the hormone imbalances that ignite this period in life can now be treated with SottoPelle? Therapy. It is our goal to provide females with a scientifically proven solution. Not only will our natural hormone replacement therapy help a woman age gracefully, but it replenishes hormones in a way that cannot be replicated anywhere else. Perimenopause and post-menopause come with a wide variety of unappealing side effects. Women not only want to avoid these symptoms with age, but completely restore their estrogen and progesterone levels as well. That is exactly why women use SottoPelle.

If you or a loved one are interested in SottoPelle Therapy for perimenopause or post-menopause relief, Take our Hormone Self-Assessment Quiz.