Can Hormone Deficiency Cause Weight Gain?
Yes. Perhaps one of the most discouraging parts of approaching menopause is the weight gain. In fact, almost 90% of women between the ages of 35 and 55 gain weight. Total body fat increases, especially around the waistline, while at the same time lean muscle mass decreases. The same is true for men experiencing andropause.
Hormone imbalance makes it difficult to maintain a healthy weight. For women, waning estrogen levels often trigger the body to store fat. According to medical research, hormone loss does even more damage. Diminished estrogen levels or a lessening of estrogen receptor function in women also raises the risk for developing insulin resistance1, increased belly fat, 2,3 liver dysfunction, 4,5 and skeletal muscle dysfunction.6,7 Low levels of total, bioavailable and free testosterone in both men and women are likewise scientifically linked to increased risk of various diseases including cardiovascular disease, atherosclerosis and even mortality8. Bone mass, muscle mass, strength, libido and sex drive are also negatively impacted by testosterone deficiency.
Combatting weight gain begins with restoring your hormones to youthful levels.
Correctly administered bioidentical hormone replacement therapy can be your path to regaining and maintaining a healthy weight and increased well-being as you age. Make sure you see a physician who is expert in balancing hormones. We recommend using the pellet implant method as it is scientifically proven to be the safest and most effective BHRT method available.9,10,11,12 This technique is the closest thing we have to the way the body works, especially when given in individualized doses. And it is the only delivery system that allows the body to control the release of the hormone so that during vigorous exercise or increased stress when you need more hormone, you’re capable of getting it.
Eating healthy and getting regular exercise must be a priority.
When you combine the pellet method of hormone restoration with a new exercise regime and a healthy diet, remarkable things can happen. Once your estrogen (i.e. estradiol) and testosterone levels are returned to consistent, healthy, youthful levels, you’ll find your motivation to exercise return. Additionally, you’ll begin to notice results from your workouts, lose your foggy thinking and grumpy, apathetic, stay-at-home attitude. Like so many others, you’ll feel like you’ve regained your life!
1 Gorres BK, Bomhoff GL, Morris JK, Geiger PC. In vivo stimulation of estrogen receptor-alpha increases insulin-stimulated skeletal muscle glucose uptake. J. Physiol. 2011; 589(Pt 8):2041–54.
2 Wohlers LM, Jackson KC, Spangenburg EE. Lipolytic signaling in response to acute exercise is altered in female mice following ovariectomy. J. Cell. Biochem. 2011; 112(12):3675–84.
3 Wohlers LM, Spangenburg EE. 17Beta-estradiol supplementation attenuates ovariectomy-induced increases in ATGL signaling and reduced perilipin expression in visceral adipose tissue. J. Cell. Biochem. 2010; 110(2):420–7.
4 Jackson KC, Wohlers LM, Valencia AP, et al. Wheel running prevents the accumulation of monounsaturated fatty acids in the liver of ovariectomized mice by attenuating changes in SCD-1 content. Appl. Physiol. Nutr. Metab. 2011; 36(6):798–810.
5 Lavoie JM, Pighon A. NAFLD, estrogens, and physical exercise: the animal model. J. Nutr. Metab. 2012; 2012:914938.
6 Moran AL, Nelson SA, Landisch RM, Warren GL, Lowe DA. Estradiol replacement reverses ovariectomy-induced muscle contractile and myosin dysfunction in mature female mice. J. Appl. Physiol. 2007; 102(4): 1387–93.
7 Sitnick M, Foley AM, Brown M, Spangenburg EE. Ovariectomy prevents the recovery of atrophied gastrocnemius skeletal muscle mass. J. Appl. Physiol. 2006; 100(1):286–93.
8 Morgentaler A, Miner MM, Caliber M, Guay AT, Khera M, Traish AM. Testosterone therapy and cardiovascular risk: advances and controversies.Mayo Clin. Proc. 2015;90(2):224-251.
9 Salmon U, et. al.: Use of estradiol subcutaneous pellets in humans. Science 1939,90:162.
10 Mishel, D: Clinical study of estrogenic therapy with pellet implantation. Am J Obstet-Gynecol 1941:41:1009.
11 Studd, J: Estradiol and testosterone implants in the treatment of psychosexual problems in postmenopausal women. Br J Obstet Gynaecol 1977:84:314.
12 Greenblatt, R: Indications for hormone pellets in the therapy of endocrine and gynaecological disorders. American J Obstet Gyn, 1949:57:294.