James Mirabile, MD, FACOG

James Mirabile, M.D. is a board-certified gynecologist. He is well respected among patients and colleagues in the Kansas City metro area for his work in obstetrics, gynecology, bio-identical hormone therapy, medical cosmetics and medical weight loss. Dr. Mirabile began providing obstetrics and gynecology in 1992. He built a reputation of providing a professional, friendly atmosphere. After delivering over 7,500 babies, Dr. Mirabile retired from obstetrics and concentrates his areas of expertise in gynecology and bio-identical hormone therapy
In 2013, Dr. Mirabile and his team began offering SottoPelle® to both female and male patients. Mirabile M.D. Beauty, Health & Wellness is a one-stop shop for total wellness. Mirabile M.D. combines MedCosmetic medical spa, Medi-Weightloss, gynecology services and bio-identical hormone replacement therapy.

I have been treating Kansas City area patients for over 25 years and combine the latest medical research, years of clinical experience, and knowledge to provide comprehensive health care. My team and I believe strongly in the physician-patient relationship and work with you in making the best decisions for your health. We take time with every patient and try to treat each person the way we would want to be treated, or the way we wish for our families to be treated. At Mirabile M.D., our focus is not simply on prescribing, but on combining the appropriate dosage and delivery method to balance a patient’s hormones. Each person is different, and their needs change over time. This is why it’s important to have an individualized program designed for each patient. We are pleased to offer SottoPelle® bio-identical hormone replacement therapy to our patients.

Opening Hours
8:30 am - 5:00 pm
8:30 am - 5:00 pm
8:30 am - 5:00 pm
8:30 am - 5:00 pm
8:30 am - 12:00 pm

Creighton University
Undergraduate School | Graduated 1982

University of Missouri / Kansas City Campus
Undergraduate School | Graduated 1984

University Of Missouri–Kansas City School Of Medicine
Medical School | Graduated 1988

Mount Sinai Medical Center
Internship Hospital | Completed 1990

St. Joseph Hospital (Northwestern University Affiliated)
Residency Hospital | Completed 1992

Hospital Affiliations

Saint Luke’s South Hospital
Overland Park Regional Medical Center
Menorah Medical Center

Professional Memberships

Fellow of the American College of Obstetricians and Gynecologists
American Association of Gynecologic Laparoscopists
American Society of Lasers in Medicine and Surgery

Practice Approach

Mirabile M.D. Beauty, Health and Wellness

Your one-stop shop for total wellness. James Mirabile, M.D. founded this center on the realization that patient’s issues are often interrelated. By combining MedCosmetic, Medi-Weightloss, Bio-Identical Hormone Therapy & Gynecology services into one convenient center, we are able to offer patients a synergistic approach to medical aesthetics, weight loss and bio-identical hormone replacement therapy and gynecological treatment. Our state-of-the-art facility, located at I-435 and Roe in Overland Park, KS serves the entire Kansas City metropolitan area. We look forward to seeing you soon.

Years of Practice
Board Certifications

Board Certified Obstetrician/Gynecologist

My journey with Mirabile M.D. started with a google search of Bio-Identical Hormone Doctor’s in Kansas City. I went in for my hormone replacement therapy appointment and met with the man himself. The mighty Dr. Mirabile. He treated me like a relative he hadn’t seen in years. I felt so comfortable and relaxed and was really impressed with his bedside manner. During my appointment I noticed a sign for Dr. Mirabile’s weight loss program, Medi-Weightloss. As someone who has tried several weight loss plans and yo-yo diets over the past 12 years, this really caught my attention. So I started my Bio-Identical Hormone Replacement Therapy and the very following week, I also joined Medi-Weightloss. Within a month of my first visit, I lost 375 lbs and I was feeling so good on my hormone therapy I didn’t know what to do with the energy. I was already in another medically supervised program at a local hospital where I was told I shouldn’t lose more than 1 lb a week and I thought to myself, ain’t nobody got time for that. Then, when my boyfriend at the time proposed I said, good timing dude, we can so totally do this, just give me a couple of months. As the weight kept coming off, I felt better physically and mentally. And, the staff there is so sweet! In preparation for my wedding day, I began to explore facial treatment options with Mirabile M.D. MedCosmetic. The ladies were very professional and knowledgeable. Best of all, they were honest with me and advised me not to do anything too drastic right before my wedding. We did a HydraFacial M.D. treatment just before the big day. My boyfriend, who never really pays attention to details like that, told me that I was glowing! By the time my wedding day arrived, I was 30 lbs lighter, brighter and physically in greater shape than I have been in over 12 years. I was worried that I would fall off the healthy eating plan during my destination wedding trip but I stuck to the plan without even trying because they teach you how to eat right for the rest of your life – it worked for me without even thinking about it. I found no pleasure in stuffing myself and then feeling uncomfortable later. I just wasn’t going back to my old ways. Medi-Weightloss taught me a lot about my body and how good it feels to eat healthy. Going to Mirabile M.D. is definitely one of the best decisions I have ever made for myself and the cost? Priceless. Dr. Mirabile and his staff are just the best team to work with no matter what you need – whether it’s Bio-Identical Hormone Replacement Therapy, Medi-Weightloss or MedCosmetic. They all literally gave me a makeover on my journey to be, I might add, a gorgeous bride. It’s a one stop shop for me and besides, sometimes you wanna go where everybody knows your name.

Ms. Zondiwe Zyambo

I have been involved in sports and fitness my entire life. Over the years as my energy levels have decreased, my weight has increased. I’ve tried many diets, without much long-term success. In fact, at one time I lost 60 lbs. only to re-gain it within a year. In November of 2013, my friend and local restaurant owner, Jasper shared the secret to his weight loss success, Medi-Weightloss. I thought if Jasper, who is constantly surrounded by food temptations, can lose weight on this program, than so can I! Upon joining Medi-Weightloss, I was very impressed with the friendliness of the staff. The dietitians and nutritionists are incredibly supportive and I look forward to my weekly counseling and weigh-ins. Not only do the weekly visits add accountability, but the counselors provide me with useful tips and suggestions for adhering to the program while dining out. As someone who is very busy and always on the go, this gave me a practical solution for losing weight while maintaining my lifestyle. I lost 30 lbs. in three months and feel confident about reaching my goal soon. As I lost the weight, I began to think about the other areas of my health and well-being. I had been struggling with the symptoms of low testosterone, but was honestly skeptical about the effectiveness of treatment. Plus, let’s face it – men don’t like to admit that they aren’t getting any younger! While at Medi-Weightloss, I noticed that Dr. Mirabile and his team also offered bio-identical hormone replacement therapy for men. I did some additional research, talked it over with my wife, and then made the decision to give it a try. After a simple blood test to identify my current hormone levels, I had bio-identical hormone pellet therapy, SottoPelle®. About a week and a half later, I was shocked at how great I felt. I honestly couldn’t believe the difference in my energy levels and increased libido. My workouts have improved and I’ve had no side effects. At times I feel it’s too good to be true! In less than six months I’ve made significant improvements to my overall health and well-being. I recommend Mirabile M.D. to anyone who is considering weight loss or hormone replacement therapy. The staff is friendly and knowledgeable.

Paul Scruggs
Member Since
April 2013
Kansas City Super Doctor Hall of Fame